Oteil Burbridge‘s long-awaited studio record, Water In The Desert, is here. The album was produced by David Ryan Harris (who spent much of 2017 on the road with John Mayer), and features some of Burbridge’s favorite players, including brother Kofi Burbridge on keys, Lil’ John Roberts and Sean O’Rourke on drums, Mark Rivers and Alfreda Gerald on vocals, Dave Yoke on guitar and Miguel Atwood Ferguson on strings.“I started writing the songs on this record about ten years ago,” says Burbridge, two-time Grammy-winning bassist, in a statement. “They are all songs about love in some way; finding out how to love yourself, hoping that another loved one will love you just as you are, believing in someone when they find it hard to believe in themselves, love gone wrong, or finally finding the “perfect fit.” I feel like every problem we have on earth in some way comes back to the lack of love. That’s really what this record is about.”“Let Oteil Sing” Campaign Brings $4K To The Gorilla Doctors Following Dead & Co’s 2017 Summer TourWith elements of funk, soul, jazz, and beyond, the concept of love is beautifully executed on the 9-track record. Even better, Oteil is bringing the music on the road with him next month for a mini Oteil & Friends tour. During his time off from Dead & Company, the bassist will be joined by JGB keyboardist Melvin Seals, Lettuce/Soulive guitarist Eric Krasno, Furthur guitarist John Kadlecik, Primus/RatDog/Electric Beethoven drummer Jay Lane, former Nth Power and current Trombone Shorty percussionist Weedie Braimah, and vocalist Alfreda Gerald for a 9-date tour this November.While Oteil & Friends were previously slated to perform a sold-out show at Le Poisson Rouge in NYC on November 9, the show was rescheduled for Dead & Company’s appearance at Band Together: Benefit Concert For North Bay Fire Relief.You can purchase Oteil Burbridge’s fantastic new record, Water In The Desert, on iTunes, Apple Music, Amazon, and listen to it below on Spotify:Oteil & Friends 2017 Tour October 31 — The Ardmore Music Hall; PANovember 1 — Pour House; Charleston, SCNovember 2 — Georgia Theatre; Athens, GANovember 3 — Salvage Station; Asheville, NCNovember 4 — Neighborhood Theater; Charlotte, NCNovember 5 — The Lincoln Theatre; Raleigh, NCNovember 6 — Fillmore; Silver Spring, MDNovember 7 — The Rex Theater; Pittsburgh, PANovember 8 — Soundstage; Baltimore, MD
A new theoretical framework outlined by a Harvard scientist could help solve the mystery of how bacterial cells coordinate processes that are critical to cellular division, such as DNA replication, and how bacteria know when to divide.For decades, scientists have believed that cellular division is triggered when bacterial cells reach a particular size. The new model, described by Ariel Amir, an assistant professor of applied mathematics and applied physics, in a paper recently published in Physical Review Letters, suggests that cells coordinate the replication of their DNA not through size, but by how much they grow over time.“The focus of this work is on how bacteria regulate their size — how do they know when to divide, so they all remain largely identical,” Amir said. “The question is: How do they do that, and how does that couple with other processes in the cell, such as DNA replication?”Scientists have long known that bacteria can double their population in as little as 20 minutes, but a series of pioneering studies in the late 1960s revealed that it takes about an hour from the time DNA replication starts until cell division occurs.The remaining mystery has been in how those two processes are coordinated.“The answer is quite remarkable,” Amir said. “Earlier studies showed that what bacteria do is actually start the DNA replication process for subsequent generations. A single bacterial cell may actually be replicating DNA for its grandchildren, or even its great-grandchildren.”In the 1960s, researchers showed that DNA replication begins when cells reach a critical size, leading to the belief that bacteria somehow know how large they are, and that DNA replication is triggered at a certain size.Later studies, however, challenged that model with the finding that the size of bacteria at birth was correlated to the size of bacteria at division. Those findings — that smaller bacteria produced smaller offspring, while that of larger bacteria was larger — suggested that bacteria were measuring something other than their size.“What I propose is something that can reconcile these two pictures in a very simple way,” Amir said. “Rather than trying to reach a critical size, cells try to add a specific volume from the initiation of DNA replication to the next replication event. To do this, the cells need to measure a difference in volume, which is much easier, and they can achieve this in a biochemical way that doesn’t include any absolute measurement.”Though the exact biochemical process hasn’t been identified, Amir suggested that it might be similar to a system described in several studies in the 1970s.“Within this hypothetical model proposed in the ’70s, one protein is found at a constant concentration throughout the cell, and as the cell grows in volume the number of new copies it makes has to be proportional to the change in volume,” Amir said. “By thresholding the number of new copies, the cell can measure a change in volume.”Ultimately, Amir said, understanding how bacteria regulate their size could spur advances on a host of questions connected to the ways cells regulate biological processes.“This is a doorway to a larger question of how cells regulate and coordinate all the processes which occur in them, which is a huge question in biology,” Amir said. “This is an example where we can quantitatively understand some aspects of that, so I think this might lead us to some broader questions.”
Here, Press Association Sport looks at some of the notable recent clashes between the sides. :: Chelsea 2 Manchester City 4 (February 27, 2010) Press Association Manchester City host Chelsea on Sunday in an early-season clash of the two most-fancied teams for the Barclays Premier League title. Wayne Bridge refused to shake John Terry’s hand over allegations of an affair with his girlfriend Vanessa Perroncel, before City beat nine-man Chelsea. Two Frank Lampard goals book-ended a calamitous afternoon for Chelsea as Carlos Tevez and Craig Bellamy each netted twice and Juliano Belletti and Michael Ballack were sent off. :: Chelsea 2 Manchester City 1 (December 12, 2011) Chelsea ended City’s unbeaten start to their first Premier League title-winning season, despite Mario Balotelli scoring inside two minutes. Raul Meireles equalised before half-time and Joleon Lescott handled in his own box to gift Chelsea their winner, the penalty scored by Lampard. :: Manchester City 2 Chelsea 1 (March 21, 2012) After six months in disgrace and self-imposed exile, Carlos Tevez returned a hero as he helped inspire a triumphant City comeback against Chelsea. It was Chelsea’s first loss under caretaker manager Roberto Di Matteo. Gary Cahill’s deflected shot put Chelsea ahead but Sergio Aguero levelled from the penalty spot before Tevez set up Samir Nasri’s 85th-minute winner. :: Chelsea 2 Manchester City 1 (October 29, 2013) Fernando Torres settled a thrilling encounter with a gift of a stoppage-time Chelsea winner after a rush of blood from City goalkeeper Joe Hart and a mix-up with defender Matija Nastasic. Chelsea boss Jose Mourinho celebrated extravagantly by going into the crowd looking for his son. Torres had earlier set up Andre Schurrle for the opener before Aguero equalised. :: Manchester City 1 Chelsea 1 (September 21, 2014) The odd sight of Chelsea’s all-time record goalscorer Lampard playing against them became even more uncomfortable for the Londoners as the veteran midfielder netted a late equaliser for 10-man City after coming off the bench. Lampard, released by Chelsea four months earlier, had joined City on a short-term deal before moving to New York. He refused to celebrate and later admitted he felt mixed emotions after cancelling out Schurrle’s opener. City earlier had Pablo Zabaleta sent off.
…AFC says it is committed to coalition politics at national levelThe Alliance For Change (AFC) has announced that it would contest the Local Government Elections without being in coalition with A Partnership For National Unity (APNU), but the People’s Progressive Party (PPP) has described this AFC move as deceitful and unscrupulous politics.Subsequent to the AFC announcement, the PPP, in a release, stated that since the AFC’s coalition with the APNU in 2015, the AFC has adopted inconsistent, flip-flopping and deceptive political postures as it struggles to survive as a relevant political force.“We have seen how it flip-flopped on many issues in the past, including the parking meter contract, VAT on education, the sugar industry; and even before they entered into the coalition, Khemraj Ramjattan is on public record saying that the AFC will never enter into a coalition with the APNU/PNC, because if it does so, it will be “dead meat”, the PPP posited.The PPP added that the AFC has consistently taken public positions on issues as it attempts to fool the populace, but its intention is only to strengthen its negotiation leverage with APNU.The PPP is of the belief that the AFC’s announcement that it would contest the upcoming Local Government Elections separate from APNU is part of a ploy.“Again, the intent can be gleaned from its public statement in which it indicated that it will not contest in all of the Local Authority areas. The trickery is that (the AFC) will come into certain PPP strongholds in which APNU will not contest, as a Trojan horse, pretending to be independent of the APNU in order to garner some sympathy votes in these areas”, the PPP added.“If they think they can pull off such clumsy stunts, (it) is illustrative of the lack of respect which they have for the intelligence of the Guyanese electorate”, the PPP said.The Opposition party has called upon every single Guyanese not to allow themselves to be used by this moribund cabal of untrustworthy politicians who are grasping at the last straw for their survival.The AFC announcement of this important decision was made on Sunday via a statement to the media. According to the minority party in the coalition Government, “This decision was reached following the inconclusive negotiations with APNU.”Efforts to contact the Chairman of the APNU, Basil Williams, for a comment on Sunday proved futile. However, the General Secretary of the People’s National Congress (PNC), the leading party in the five-member APNU coalition, Amna Ally, told the Guyana Times that she found out about AFC’s decision in a newscast.Meanwhile, the AFC said this separation applies only for the 2018 Local Government polls, and “does not, in any way, affect the APNU+AFC Coalition Government, nor does it, in any way, change the AFC’s position on coalition politics at the national level. The AFC remains, and reaffirms that it is, committed to the APNU+AFC Coalition.”Following its decision, the party’s Management Committee has since resolved into the LGE Campaign Committee and is chaired by Executive Member David Patterson, who has been appointed Campaign Director. Additionally, Juretha Fernandes has been appointed Deputy Campaign Director, while appointments to other positions will be done subsequently.“The AFC is in full preparation mode for LGE, including hosting meetings in the various constituencies and identifying potential candidates who will be subject to a rigorous internal vetting process before official appointment. Candidates will be addressing the local issues which are of concern to citizens, and working collaboratively to find practical and implementable solutions,” Sunday’s missive stated.It further outlined that the AFC will soon determine which municipalities and constituencies it would strategically contest, as it does not envision contesting in each Neighbourhood Democratic Council and in every constituency of all municipalities, until subsequent election cycles.“The AFC is confident in the support it will continue to receive from the people of Guyana, and can assure citizens that it will only nominate candidates of the highest calibre and quality,” the party noted.On February 14 last, the APNU and AFC celebrated their 3rd year anniversary since signing the “lovers’ deal”.However, the AFC of recent has come under fire for the submissive role it has been playing since joining forces with the APNU. In fact, the top leadership of the AFC had decided back mid-November to revise its governing agreement with its majority coalition partner.The Cummingsburg Accord has a lifespan of a minimum of three years and maximum of five years, and was focused primarily on the General and Regional Elections.To this end, the AFC had proposed as part of the nine points up for negotiation with its coalition partner that an agreement on LGE be crafted. In fact, the minority coalition partner detailed some of its positions for negotiation in the LGE Accord. The AFC’s NEC, after a May 1 meeting, had allowed additional time for the two coalition partners to have a definitive written agreement in the form of a Local Government Elections Accord.